The Atwima Mponua District is located in the south-western part of the Ashanti Region covering an area of approximately 894.15 square kilometers. It lies between longitude 2o00’W and 2*32’W and latitude 6o32’N and 6o75’N.

The District shares boundary with eight Districts, principally in the South with the Amansie West District, Ahafo Ano South to the north, Atwima Nwabiagya in the East and Bibiani – Anwhiaso – Bekwai District of the Western Region. Nyinahin, the capital is more in the west of the west of the District, about 45km from Kumasi.