The district is located in the equatorial climate zone. Temperatures are uniformly high throughout the district and rainfall is heavy. The combination of the two translates into high relative humidity. The district falls within the equatorial rain forest.

The natural vegetation is the moist semi-deciduous forest. There are various tree species of economic value. The district is endowed with rich forest ochrosols, conducive to the cultivation of both industrial and food crops. Forest oxysols are found around Sefwi Bekwai-Awaso area. These are rich in bauxite deposits extensively mined in the district.