The District is located in the middle part of the Western Region of Ghana. It lies between latitudes 5, 30` N, 6, 15` N, longitudes 1, 45` W, and 2, 11` W. It has an estimated total land area of about 16000 square kilometers; about 8% of the size of the region.
It is bounded to the west by Wassa Amenfi West; to the East by Mpohor Wassa East, to the North by Upper and Lower Denkyira and to the south by Wassa West District.
Members of the Wassa Amenfi East District Assembly in the Western Region have re-elected Mr. Stephen Mensah Kwofie as the Presiding Member of the Assembly at Daboase
The Japanese Embassy in Ghana has provided a US8, 891.00 grant for the construction of a six-unit classroom block for the Aserewadi Primary School in the Amenfi East District of the Western Region.
About 200 houses including other assorted items have been destroyed by a heavy downpour in Wassa Akropong in the Wassa Amenfi East of the Western Region rendering over 500 residents homeless.
The volume of water supply to the Sekondi-Takoradi Metropolis has been reduced by 50 percent due to the collapse of the operational facility at the Daboase Water Works in the Western Region.