Asikuma-Odoben-Brakwa District is one of the newly created districts of Ghana, located in the north-central portion of the Central Region of Ghana. The district was curved out of the former Breman-Ajumako-Enyan-Essiam District, in 1989. Its capital is Breman Asikuma.
The District covers a geographical area of 884.84 square kilometres. It is sandwiched between 4 main districts, at a uniform radius of about 40 kilometers apiece from each of them, except Ajumako, which is 25 kilometers away. On the northern border is the Birim South District of the Eastern border lies the Agona District and the Ajumako-Enyan-Essiam District is on the Southern border.