Kwabre East District, carved out of the former Kwabre Sekyere District in 1988, is located almost in the central portion of the Ashanti region. It is within latitudes 60 44’ North and longitudes 10 33’ to 1044’ West. The District shares common boundaries with Afigya Sekyere District to the North; Kumasi Metropolitan Area to the South; Ejisu Juaben Municipal to the Southeast; Atwima District to the West and Offinso Municipal to the Northwest. The District has a total land area of 246.8 square kilometres constituting about 1.01% of the total land area of Ashanti Region. Kwabre East District is part of the greater Kumasi City region, which is made up of Kumasi Metropolitan Area and the surrounding Districts
The District capital, Mamponteng, is approximately 14.5 kilometres from Kumasi to the north east. There are 86 settlements, administered under 3 paramountcies, 2 parliamentary constituencies, 11 Area Councils and 42 District electoral areas.
District Public Health Assistant at the Kwabre East District in the Ashanti Region, Mrs. Hellen Aovare has disclosed that for the past three years, there has not been any recorded case of maternal mortality in any of the health facilities in the district.