The district is located in the south-western part of the Ashanti Region. It shares common boundary on its Western part with the Atwima District. On its northern part can be found the Bosomtwe District, while a regional boundary separates it from Western Region on its southern part. Manso Nkwanta is the capital.
The population of the district according to the 2010 Population and Housing Census stands at 134,331 with 67,485 males and 69,790 females.
The church of Jesus Christ of Later day saints has provide boreholes to eleven communities at a ceremony held at Manso Suntreso in the Amansie West District of Ashanti Region at the cost of 320,000.00.
A sod cutting ceremony for the construction of 3 classroom block, office, store and toilet facilities for the Manso Nyankomasi Islamic Primary School in the Amansie West District of Ashanti Region has taken place at Manso Nyankomasi.