The district is located in the south-western part of the Ashanti Region. It shares common boundary on its Western part with the Atwima District. On its northern part can be found the Bosomtwe District, while a regional boundary separates it from Western Region on its southern part.
The District Chief Executive for Amansie West, Mr. Alex Kwame Bonsu, has bemoaned the spate of illegal mining, indicating that the former had gained root such that it was difficult for the Assembly to stop the youth from engaging in it.
Keegan Resource Ghana Limited (KRGL), a mining firm, has provided a 20-seater aqua privy toilet facility, a medical laboratory, and a 3-unit Kindergarten school block for three communities in the Amansie West District.